Plant Transcription Factor Database
Previous version: v3.0
Citrullus lanatus
ARF Family
Species TF ID Description
Cla000557ARF family protein
Cla001900ARF family protein
Cla005790ARF family protein
Cla008736ARF family protein
Cla009652ARF family protein
Cla009800ARF family protein
Cla011357ARF family protein
Cla012819ARF family protein
Cla013766ARF family protein
Cla015002ARF family protein
Cla016872ARF family protein
Cla018293ARF family protein
Cla019321ARF family protein
Cla019548ARF family protein
Cla020817ARF family protein
ARF Family Introduction

Auxin response factors (ARF) are transcription factors that regulate the expression of auxin response genes. ARFs bind with specificity to TGTCTC auxin response elements (AuxRE) in promoters of these genes and function in combination with Aux/IAA (auxin/indole acetic acid) repressors, which dimerize with ARF activators in an auxin-regulated manner.

Most ARFs consist of an amino-terminal DNA-binding domain (DBD), a middle region that functions as an activation domain (AD) or repression domain (RD), and a carboxy-terminal dimerization domain (CTD). The ARF DBD is classified as a plant-specific B3-type, but requires additional amino-terminal and carboxy-terminal amino acids for efficient in vitro binding to TGTCTC AuxREs.

The ARF ADs and RDs are located just carboxy-terminal to the DBDs and contain biased amino acid sequences. ARF ADs are enriched in glutamine along with serine and leucine residues, while ARF RDs are enriched in serine, proline, leucine and glycine residues.

Guilfoyle TJ, Hagen G.
Auxin response factors.
Curr Opin Plant Biol, 2007. 10(5): p. 453-60.
PMID: 17900969